Spotlight on: HRT and dementia

Dr  Sarah Glynne graduated from Imperial College School of Medicine with Honours in 1999. She qualified as a member of the Royal College of Physicians in 2002, and the Royal College of General Practitioners in 2008. In 2016 she was awarded a Master of Science degree in immunology and allergy. 

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Dr Glynne is a GP Menopause Specialist. In addition to her clinical practice, she holds an academic position at Newson Health where she contributes to research and education.

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Dr Glynne is particularly interested in the link between Covid-19 and hormone imbalance. Hormonal perturbations are a major barrier to recovery in many female patients with long Covid, and hormone therapy (HRT) can significantly improve health and quality of life. She is also interested in the management of menopausal symptoms in women with a history of breast cancer. She is keen to promote access to evidence-based care for breast cancer survivors and support women to make informed decisions about their treatment options.  

Dr Kejal Kantarci is Katherine B. Andersen Endowed Professor in Women’s Health, and Professor of Radiology in the Division of Neuroradiology at Mayo Clinic Rochester. She is the Director of the Women’s Health Research Center, Associate Director of the Mayo Clinic Alzheimer’s Disease Research Center; and Principal Investigator of the Building Research Careers in Women’s Health (BIRCWH) K12 Program. Her research focuses on the neuroimaging, neuroscience and clinical aspects of aging and dementia, particularly in women’s cognitive health and Lewy body dementias.

Dr. Kantarci is a member of the Society of Women's Health Research Alzheimer 's Disease Network and member of the Dementia with Lewy Bodies Scientific Advisory Council.  Currently, she is leading an National Institutes of Health (NIH)-funded multi-center program on determining the long-term effects of early menopausal hormone therapy on Alzheimer’s pathophysiology (Overview - KEEPS Continuation Study - Mayo Clinic Research).

She received the Beeson award from the NIA/NIH in 2007, de Leon Prize in Neuroimaging Senior Scientist Award from the Alzheimer’s Association in 2018, was selected the Senior Fellow of the International Society of Magnetic Resonance in Medicine in 2021. Dr Kantarci Chaired the Alzheimer’s Association International Conference in 2019 and was the Co-chair NIH Alzheimer's Disease Related Dementias (ADRD) 2022 Summit on Lewy Body dementias. Dr Kantarci is a member of Leaders Empowering the Advancement of Diversity in Education, Research and Science (LEADERS) in the Health of Women. 

Dr Pauline M Maki is Professor of Psychiatry, Psychology and Obstetrics and Gynecology; Director of the Women’s Mental Health Research Program, and Associate Dean for Faculty Affairs at the University of Illinois at Chicago (UIC). For the past 25 years, she has led a program of research on women’s health, particularly women’s mental and cognitive health. She has over 200 scientific publications on this topic. Her research addresses important issues in women’s health such as how hormonal changes and menopause symptoms affect women’s cognition, brain function and mood at midlife and the effect of menopausal hormone therapy on cognition and mood.

Dr Maki is Past President of the North American Menopause Society (NAMS), Treasurer of the International Menopause Society, and past Chair of the Society for Women’s Health Research Interdisciplinary Network on Alzheimer’s Disease. She won the 2018 Woman in Science Award from the American Medical Women’s Association, the Thomas B. Clarkson Outstanding Clinical and Basic Science Research Award from the NAMS, and the 2023 Health Education Visionary Award from the Society for Women’s Health Research. She has won several National Institutes of Health (NIH) awards for her research and service, serves as a research and career mentor to many students and junior faculty, serves on executive committees for several women’s health advisory boards, and is a frequent international and national speaker.

Her work is widely cited in the media, including in such outlets as the New York Times, Wall Street Journal, Washington Post, Fox News, National Public Radio, BBC, Woman’s Hour, the Today Show, NBC News, ABC News, and the Guardian. Her work on mental health in pregnancy and the postpartum has received accolades from the Kennedy Forum, the news media, and the Office of the Vice President of the United States.