About this event

  • Date and time Tue 21 Jan 2025 from 8:15am to 22 Jan 2025 at 5:00pm
  • Location Royal Society of Medicine
  • Organised by Pathology, Pathological Society of Great Britain and Ireland

Gain insight into the cellular changes observed in disease and how these changes may be modelled to allow better understanding of disease at this upcoming event. Bridging the gap between cellular changes, and the manifestation and treatment of disease, leading researchers will describe how changes in the immune system and in the vasculature may vary with time and be harnessed to treat disease. They will also explain new models for both neoplastic and non-neoplastic diseases, and how combining data from different sources can give a complete picture of a disease.

This event will bring together pathologists, scientists, front-line clinicians, trainees and undergraduate students to create a stimulating academic environment. Through a mixture of state-of-the-art lectures and presentation of cutting-edge research, delegates will gain up to date knowledge and learn about the latest advances in pathology research.

By attending, you will:

  • Learn about changes in the immune system in different disease processes and how these can be harnessed to fight disease
  • Learn about the latest methods of in-vitro tissue culture to model normal tissue and disease
  • Learn about the integration of multiplatform data in disease

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Tickets

Early Bird pricing available until 20 December 2024.

Member

RSM Fellow
Day 1
£175.56 Meeting - Day 1
£175.56 Meeting - Day 2
£70.00 Dinner
RSM Associate
Day 1
£70.00 Dinner
£58.48 Meeting - Day 1
£58.48 Meeting - Day 2
RSM Retired Fellow
Day 1
£70.00 Dinner
£58.48 Meeting - Day 1
£58.48 Meeting - Day 2
RSM Trainee
Day 1
£70.00 Dinner
£55.65 Meeting - Day 1
£55.65 Meeting - Day 2
RSM Student
Day 1
£30.00 Meeting - Day 1
£30.00 Meeting - Day 2
£25.00 Dinner

Non - Member

Consultant / GP / SAS Doctors
Day 1
£304.29 Meeting - Day 1
£304.29 Meeting - Day 2
£70.00 Dinner
Path Soc Ordinary
Day 1
£175.56 Meeting - Day 1
£175.56 Meeting - Day 2
£70.00 Dinner
AHP / Nurse / Midwife
Day 1
£97.02 Meeting - Day 1
£97.02 Meeting - Day 2
£70.00 Dinner
Trainee
Day 1
£97.02 Meeting - Day 1
£97.02 Meeting - Day 2
£70.00 Dinner
Path Soc Retired
Day 1
£70.00 Dinner
£58.48 Meeting - Day 1
£58.48 Meeting - Day 2
Path Soc Concessionary
Day 1
£70.00 Dinner
£55.65 Meeting - Day 1
£55.65 Meeting - Day 2
Student
Day 1
£70.00 Dinner
£48.51 Meeting - Day 1
£48.51 Meeting - Day 2
Path Soc Student / Foundation Doctors
Day 1
£30.00 Meeting - Day 1
£30.00 Meeting - Day 2
£25.00 Dinner

Agenda

View the programme - Day 1 21 January 2025

Registration, tea and coffee
Welcome and introduction

Dr Matthew Pugh, Pathologist, University of Birmingham

Symposium 1: The disease microenvironment: Part 1 Spatial profiling

Chairs: Professor Paul Murray, Royal College of Surgeons Ireland (Medical University of Bahrain) and University of Limerick, Ireland and University of Limerick, Ireland and Dr Matthew Pugh, Pathologist, University of Birmingham

Spatial profiling in lymphoproliferative disorders

Professor Paul Murray, Professor of Molecular Pathology, Royal College of Surgeons Ireland (Medical University of Bahrain)

Spatial profiling in Sjogren's disease

Professor Andrew Filer, Professor of Translational Rheumatology, Inflammation and Aging, University of Birmingham 

Analysis of multi-omic spatial data

Dr Trevor McKee, Co-founder and Chief Executive Officer, Pathomics.io

Tea and coffee break

Poster viewing and trade exhibition

Symposium 1: The disease microenvironment: Part 2 Impact on biology

Chairs: Professor Gary Middleton, University of Birmingham and Professor Christian Münz, University of Zürich

Epstein Barr Virus and multiple sclerosis

Professor Christian Münz, Professor and Co-Director of the Institute, Institute of Experimental Immunology, University of Zürich, Switzerland 

High endothelial venules and tertiary lymphoid structures in cancer

Professor Gabriele Bergers, Head of the Laboratory of Tumour Microenvironment and Therapeutic Resistance, Vlaams Instituut voor Biotechnologie, Leuven, Belgium  

Circadian anti-tumour immune responses

Professor Christoph Scheiermann, Department of Pathology and Immunology, University of Geneva, Switzerland

Lunch

Poster round and trade exhibition

13:00: Formal poster round

Plenary session

Chairs: Professor Mohammad Ilyas, University of Nottingham and Professor Louise Jones, Queen Mary University London

Spatial transcriptomics delineates tumour heterogeneity in pre-NACT Triple-Negative Breast Cancers

Isobelle Wall

Intestinal stromal populations are differentially expanded according to cancer cell TGF-beta pathway mutations

William Dalleywater

Spatial transcriptomic characterisation of the human bone marrow

Rosalin Cooper

Neurofibromatosis type 1 is associated with extensive, independent second <I>NF1</I> hits within morphologically normal tissues

Thomas Oliver

Modulation of lifespan in ALS/FTD drosophila models via stress granule gene expression regulation

Charles Amsellem

Machine learning achieves pathologist-level coeliac disease diagnosis

Elizabeth Sollieux

Tea and coffee break

Poster viewing and trade exhibition

Announcement: Jeremy Jass Prize for Research Excellence in Pathology

Chair: Professor Louise Jones, Queen Mary University London

Goudie Lecture

Chair: Professor Mark Arends, University of Edinburgh 

Characterising Ductal Carcinoma in-situ of the breast: Will we ever be able to safely stratify care?

Professor Louise Jones, Queen Mary University London

Closing remarks

Professor Mohammad Ilyas

Close of meeting

Conference dinner

Presentation of Plenary prize and poster prizes

Location: Bunga Bunga Covent Garden, 167 Drury Ln, London WC2B 5PG

Entertainment from 10pm

Registration closes: 6 January 2024

Dress code: Smart casual

View the programme - Day 2 22 January 2025

Registration, tea and coffee

Symposium 2 (Trainees): Models of inflammation and infection

Chairs: Dr Abhik Mukherjee, University of Nottingham and Dr Hattie Hunter, Gloucestershire Hospitals NHS Foundation Trust

Mini Kidneys: Modelling of Renal Pathology

Professor Sue Kimber, Professor of Stem Cells and Development in the Faculty of Life Sciences, University of Manchester

Models of host-pathogen interactions at gut mucosal surfaces

Dr Neil McCarthy, Senior Lecturer in mucosal immunology, The Blizard Institute, Queen Mary University of London 

Mini-placentas: Exploring pre-eclampsia and pregnancy disorders

Professor Ashley Moffett, Department of Pathology, University of Cambridge

Tea and coffee break

Poster viewing and trade exhibition 

Symposium 2 (Trainees): Models of inflammation and infection

Chairs: Dr Abhik Mukherjee, University of Nottingham and Dr Sarah Ruane, Christie Hospital, Manchester

Cardiovascular disease: Stem Cell Research

Professor Chris Denning, Professor of Stem Cell Biology, University of Nottingham, Director of the University of Nottingham Biodiscovery Institute 

Machine learned feature selection for the diagnosis of complex conditions

Professor Dennis Wang, Chair in Data Science, Imperial College London, Agency for Science, Technology and Research (A*STAR Singapore)

Wyllie Lecture

Chair: Professor Mark Arends, University of Edinburgh 

Clinical trials: Where molecular pathology can advance oncology

Dr Susan Richman, University of Leeds

Lunch

Poster viewing and trade exhibition

Announcement: Paola Domizio award

Chair: Dr Abhik Mukherjee

Rapid fire oral presentations

Chair: Professor Sarah Coupland, President Pathological Society
RCPath Registrar, Senior Consultant Histopathologist, George Holt Chair of Pathology, University of Liverpool

Colorectal cancer conditioned stroma induces reciprocal changes in tumour molecular phenotypes

William Dalleywater

Complex structural variants underlie tumoural heterogeneity and defines poor survival in GBM patients

Alhafidz Hamdan

Reading between the lines - targeted metagenomic next generation sequencing (mNGS) detection of pathogens not covered in multiplex PCR in paediatric severe acute respiratory infections (SARIs)

Cheng Tsz Kin Mark

Experimental ploidy validation through Flow Cytometry identifies cryptic whole-genome doubling events in sarcomas

Thomas Butters

Symposium 3: Advances in immunotherapy

Chairs: Professor Elizabeth Soilleux, University of Cambridge and Jonas Dippel, Technical University of Berlin

Response and toxicity in checkpoint inhibition

Professor Gary Middleton

Tumour infiltrating lymphocytes as therapy

Professor Andrew Sewell, Division of Infection and Immunity, Mechanisms of Immunity Theme Lead, Systems Immunity Research Institute, Cardiff University, Wales

Tea and coffee break

Symposium 4: Pathology and big data

Chairs: Professor Elizabeth Soilleux, University of Cambridge and Jonas Dippel, Technical University of Berlin

Foundation models in Pathology

Jonas Dippel, PhD Student, Technical University of Berlin, Germany

The "Digital Twin" in cancer prediction

Dr Olivier Gevaert, Associate Professor of Medicine and Biomedical Data Science, Biomedical Informatics Research, Stanford University, United States of America

Closing remarks

Professor Mohammad Ilyas

Close of meeting

Location

Royal Society of Medicine, 1 Wimpole St, Marylebone, London, W1G 0AE, United Kingdom

Registration for this event will close at 1:00am on Monday 20 January 2025. Late registrations will not be accepted.

The agenda is subject to change at any time

If the event is recorded, we are only able to share presentations that we have received permission to share. There is no guarantee that all sessions will be available after the event, this is at the presenter’s and RSM’s discretion.

All views expressed at this event are of the speakers themselves and not of the Royal Society of Medicine, The Pathological Society, nor the speaker's organisations.