About this event

  • Date and time Tue 31 Jan 2023 from 8:00am to 30 Jan 2023 at 10:00pm
  • Location Royal Society of Medicine
  • Organised by Pathology, Pathological Society of Great Britain and Ireland

Join us for this in-person event bringing together pathologists, scientists, trainees and undergraduate students in a stimulating academic environment. Attendees will gain up to date knowledge and learn about the latest advances in pathology research. The event provides a unique environment to hear from and talk to researchers who are world renowned experts in their field. Additionally, the event also provides an opportunity for attendees to network with their peers.  

Click here to view a quick guide on how to register.

The aims of the event are to promote an understanding of disease through, exploration of tissues and disease models using single cell analyses, use of cutting edge microscopic and sequencing technologies, and maximising tissue interrogation by computational pathology and artificial intelligence. 
Benefits of attending: 
  • Understand the principles behind single cell sequencing
  • Learn about the power of high resolution microscopy   
  • Know about the role of digital technologies and AI in neoplastic and non-neoplastic pathology    

 

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Agenda

Day 1 31 January 2023

Registration, tea and coffee
Welcome and introduction

Symposium 1: Single cell

Chaired by: Dr Luiza Moore, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom and Dr Sam Behjati, Wellcome Sanger Institute, Cambridge, United Kingdom 

Introduction to single cell sequencing

Dr Sam Behjati

Somatic mutations in normal human cells

Dr Luiza Moore

Single cell epigenomics and human cancer

Dr Celine Vallot, Institut Curie 

Mapping the rules of glioblastoma using spatial genomics

Dr Omer Bayraktar, Wellcome Sanger Institute, Cambridge, United Kingdom

Open discussion
Tea and coffee break and poster viewing
Chairman’s poster rounds

Symposium 2: Building partnerships in pathology

Chaired by: Dr Kate Marks, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom and Dr Abhik Mukerhjee, University of Nottingham, Nottingham, United Kingdom

Integrating pathology in clinical trials

Dr Nick West, University of Leeds, Leeds, United Kingdom

Developing pathology-industry collaborations

Professor Clare Verrill, University of Oxford, Oxford, United Kingdom

How to establish successful public engagement in projects/trials

Ms Penny Fletcher, The Royal College of Pathologists 

Questions and answers
Lunch and poster viewing

Symposium 3: Recent advances in pathology

Chaired by: Professor Simon Herrington, University of Edinburgh, Edinburgh, United Kingdom and Dr Richard Poulsom, The Pathological Society 

Lineage tracing methods for human tissues

Professor Trevor Graham, Institute of Cancer Research, London, United Kingdom

Single cell genomics, genome complexity and cancer evolution

Dr Nischalan Pillay, University College London, London, United Kingdom

Of microbes and malignancies – the relationship between the gut microbiome and cancer response/toxicity to immune checkpoint inhibitors

Dr Ashray Gunjur, Wellcome Sanger Institute, Cambridge, United Kingdom

An update on cancer-associated fibroblasts

Dr Angus Cameron, Barts Cancer Institute, London, United Kingdom

Open discussion
Tea and coffee break and poster viewing

Plenary oral presentations

Chaired by: Professor Heike Grabsch, University of Leeds, Leeds, United Kingdom and Professor Louise Jones, Queen Mary University London, London, United Kingdom

High-grade gliomas occurring in teenagers and young adult patients comprise novel molecular subgroups

Dr Matthew Clarke, University College London Hospitals NHS Foundation Trust, London, United Kingdom

Multiple-instance-learning-based detection of coeliac disease in histological whole-slide images

Dr Jim Denholm, University of Cambridge, Cambridge, United Kingdom

Artificial intelligence- (AI) assisted evaluation of tumour infiltrating CD3+ and CD8+ T cells in the tumour core (CT) and invasive margin (IM) for prognostication and prediction of benefit from adjuvant chemotherapy in early stage colorectal cancer (CRC): A retrospective analysis of the QUASAR trial

Dr Christopher Williams, University of Leeds, Leeds, United Kingdom

Novel proliferation regulators identified using predictive bioinformatic approaches

Dr Asmaa Ibrahim, University of Nottingham, Nottingham, United Kingdom

Clonal trajectory to chronic myeloid leukaemia

Miss Aleksandra Kamizela, Brighton and Sussex Medical School, United Kingdom 

Loss of key driver mutations in <I>IDH1<I> in metastatic chondrosarcoma

Dr William Cross, University College London Cancer Institute, London, United Kingdom 

Jeremy Jass Prize for Research Excellence in Pathology in 2020

Presented by Professor Louise Jones, Editor-in-Chief, The Journal of Pathology

Close of day
Drinks reception

held at the Royal Society of Medicine

Day 2 01 February 2023

Registration, tea and coffee

Jean Shanks and Pathological Society Symposium - Guy Whittle Auditorium
Undergraduate Day - Max Rayne Auditorium
Chaired by: Professor Gareth Thomas, University of Southampton, Southampton, United Kingdom and Professor Mark Arends, University of Edinburgh, Edinburgh, United Kingdom
Chaired by: Miss Jane Ganeshalingam and Xinrui Ma
8:30am - Welcome and introduction

Professor Gareth Thomas, University of Southampton, Southampton, United Kingdom

8:30am - Welcome and introduction

Path Soc Undergraduate Committee

8:40am - Illuminating the complex rearrangement landscape of sarcoma

Dr Sara Waise, Francis Crick Institute, London, United Kingdom

8:35am - An introduction to digital pathology

Dr Clare McGenity, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

9:10am - Disentangling strand interactions in DNA damage and repair

Dr Sarah Aitken, University of Cambridge, Cambridge, United Kingdom

9:40am - Investigating the colorectal cancer-associated faecal microbiome

Dr Caroline Young, University of Leeds, Leeds, United Kingdom

9:30am - Trainee’s experience in digital pathology

Dr Charlotte Spencer, The Crick Institute, London, United Kingdom

10:10am - Next-generation diagnosis of EBV+ Hodgkin-like lymphoproliferative disorder

Dr Matthew Pugh, University of Birmingham, Birmingham, United Kingdom

10:30am - Investigating the role of intestinal Microfold (M) cells in Crohn's disease pathogenesis

Dr Alex Cavanagh, University of Edinburgh, Edinburgh, United Kingdom

10:10am - An introduction to molecular pathology

Dr David Moore, University College London, London, United Kingdom

10:50am - Closing summary

Professor Gareth Thomas

10:55am - Tea and coffee break and poster viewing
10:55am - Tea and coffee break
Symposium 4: How to explore the microscopic world

Chaired by: Professor Phil Quirke and Dr Susan Richman, University of Leeds, Leeds, United Kingdom

11:20am - Breaking into nanoimaging on routine FFPE tissue

Dr Scarlet Brockmoeller, University of Leeds, Leeds, United Kingdom

11:20am - Trainee’s experience in molecular pathology

Dr Seung Hyun Lee, Cancer Research UK Manchester Institute, Manchester, United Kingdom

11:40am - Using infrared and raman hyperspectral imaging coupled with machine learning to improve pathology prediction: Current state-of-the-art and future directions

Professor Peter Gardner, The Manchester Institute of Biotechnology, Manchester, United Kingdom

11:45am - Insight into histopathology training

Dr Kate Marks, University of Leeds, Leeds, United Kingdom

12:00pm - Theia: A virtual reality cancer research lab for visualisation, analysis and collaboration

Mr Owen Harris, Suil Interactive 

12:20pm - Open discussion
12:20pm - Questions and answers
12:35pm - Lunch break and poster viewing
12:35pm - Lunch break
1:15pm - Chairman's poster rounds
1:15pm - Chairman’s poster rounds
Symposium 5: What can we learn from sequencing

Chaired by: Professor Mark Arends, University of Edinburgh, Edinburgh, United Kingdom and Dr David Adams, Wellcome Sanger Institute, Cambridge, United Kingdom

2:15pm - Cancer driver gene mutations

Dr Andrew Lawson, Wellcome Sanger Institute, Cambridge, United Kingdom

2:15pm - Life as district general hospital pathologist

Dr Angus McGregor, Leicester Royal Infirmary, Leicester, United Kingdom

2:35pm - Uncovering the origins of paediatric cancers

Dr Thomas Oliver, Wellcome Sanger Institute, Cambridge, United Kingdom

2:35pm - Life as a tertiary centre pathologist

Dr Max Robinson, NovoPath, Newcastle, United Kingdom

2:55pm - Dermatlas: The genomic atlas of dermatopathology

Dr David Adams

2:55pm - Life as a research group leader and pathologist

Dr Elizabeth Soilleux, University of Cambridge, Cambridge, United Kingdom

3:15pm - Open discussion
3:15pm - Questions and answers
3:30pm - Tea and coffee break and poster viewing
3:30pm - Tea and coffee break and poster viewing
Symposium 6: Molecular pathology in non-neoplastic diseases

Chaired by: Natasha Cutmore, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom and Dr Tim Kendall, University of Edinburgh, Edinburgh, United Kingdom

Undergraduate oral presentation competition
4:00pm - Molecular pathology in renal transplantation

Dr Candice Roufosse, Imperial College London, London, United Kingdom

4:00pm - Relationship between the Warburg effect in tumour cells and the tumour microenvironment in colorectal cancer patients: Results from a large multicentre study

Mr Jorn Steeghs, Maastricht University, Maastricht, Netherlands

4:20pm - Molecular pathology in non-neoplastic Interstitial lung disease

Professor Ling-Pei Ho, University of Oxford, Oxford, United Kingdom

4:15pm - Exposure to enterotoxigenic bacteroides fragilis (ETBF) bacteria found in association with colorectal cancer increases clonal mutations in mice

Mr Harry Hall, University of Birmingham, United Kingdom

4:40pm - Molecular pathology in non-neoplastic hepatobiliary disease

Professor Alberto Quaglia, University College London, London, United Kingdom

4:30pm - Investigating the effects of irradiation on the peritumoral microvasculature in glioblastoma multiforme

Mr Arslan Shakeel, Hull York Medical School, York, United Kingdom 

5:00pm - Molecular pathology in infectious disease

Dr Charlene Rodrigues, Imperial College Healthcare NHS Trust, London, United Kingdom

4:45pm - Morphological comparison of colon cancer resection specimens derived from two Leading surgical techniques: Japanese D3 and european complete mesocolic excision with central vascular ligation

Mr Ross Jarrett, Leeds Institute of Medical Research, Leeds, United Kingdom

5:20pm - Questions and answers
5:00pm - Deep learning segmentation of picrosirius red staining for the assessment of collagen deposition in pre-clinical models of cancer

Mr Leshanth Uthayanan, Institute of Cancer Research

5:25pm - Closing remarks
5:15pm - Vascular remodelling and structural changes in placentas of pregnant mice infected with various pathogens

Miss Yasmin Adewusi, University of Cambridge, Cambridge, United Kingdom

5:30pm - Close of day
5:30pm - Close of day
Society dinner

Pre-booked only 

Being held at The Brewery (52 Chiswell Street, London, EC1Y 4SD)

Day 3 02 February 2023

Registration, tea and coffee

Symposium 7: Principles of computational pathology

Chaired by: Dr Jakob Kather, Dresden University of Technology, Dresden, Germany and Dr Julien Calderaro, Henri Mondor Hospital, Paris, France

Digital pathology: The broader integration

Professor Manuel Salto-Tellez, Queen’s University Belfast, Belfast, United Kingdom

A brief history of end-to-end AI in computational pathology

Dr Jakob Kather

Quality control of whole slide images in computational pathology

Dr Lisa Browning, John Radcliffe Hospital, Oxford, United Kingdom

Explainability in pathology AI

Mara Graziani, IBM Research Zurich

Open discussion
Tea and coffee break and poster viewing

Free oral presentations

Chaired by: Professor Mark Arends, University of Edinburgh, Edinburgh, United Kingdom and Professor Mohammad Ilyas, University of Nottingham, Nottingham, United Kingdom

Predicting soft tissue tumours diagnoses with deep learning

Dr Mikaël Simard, University College London, London, United Kingdom

Inflammatory pathology in human motor neuron disease

Dr Bridget Ashford, Sheffield Institute for Translational Neuroscience, Sheffield, United Kingdom

Spatial evolution of ductal carcinoma in-situ precludes accurate risk stratification on biopsy alone

Dr Philip Elliott, Barts Cancer Institute, London, United Kingdom

Label-free imaging of fresh human tissue and clinical application for histopathology

Dr Matsui Takahiro, Osaja University, Japan 

Quantifying the accumulation of clonal mutations in colorectal epithelium from patients who develop cancer compared to those without

Dr Kate Marks, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

pTERT mutation in the risk-stratification of solitary fibrous tumours

Dr Thomas Butters, University College London Cancer Institute, London, United Kingdom

A mouse model of PTEN Hamartoma Tumour Syndrome (PHTS): insights into the pathology and genomics of PTEN as a tumour suppressor and utilisation for pre-clinical tumour prevention drug testing

Dr Victoria Rathbone, University College London, London, United Kingdom

Development of a comprehensive assay for the molecular profiling of cancer by target enrichment from FFPE specimens

Dr Shinji Kohsaka, National Cancer Centre Research Institute, Japan

The Pathological Society of Great Britain and Ireland 16th Goudie Lecture - How I learned to stop worrying and love genomics

Professor Jorge Reis-Filho, Memorial Sloan Kettering Cancer Center, New York, United States of America

Chaired by: Sarah E Coupland, Pathological Society and University of Liverpool, Liverpool, United Kingdom

Lunch break and poster viewing
The Royal College of Pathologists Neera Patel Lecture - Exploring sex differences in the breast cancer microenvironment

Professor Valerie Speirs, University of Aberdeen, Aberdeen, United Kingdom

Chaired by: Sarah E Coupland

Symposium 8: Applied computational pathology

Chaired by: Dr Ralf Huss, University Hospital Augsburg, Augsburg, Germany and Professor Sabine Leh, Haukeland University Hospital, Bergen, Norway

Applications of AI in liver pathology

Dr Julien Calderaro

The rational of digital pathology in prostate cancer

Dr Ralf Huss

AI in renal pathology

Sabine Leh

Pros and cons of AI in diagnostic pathology

Professor Paul van Diest, University Medical Center Utrecht, Utrecht, Netherlands

Open discussion
Close of meeting

Location

Royal Society of Medicine, 1 Wimpole St, Marylebone, London, W1G 0AE, United Kingdom

Registration for this event will close at 1:00am on Monday 30 January 2023. Late registrations will not be accepted.

Disclaimer:

  • The agenda is subject to change at any time
  • If the event is recorded, we are only able to share presentations that we have received permission to share. There is no guarantee that all sessions will be available after the event, this is at the presenter’s and RSM discretion.
  • All views expressed at this event are of the speakers themselves and not of the Royal Society of Medicine, nor the speaker's organisations.
  • This event will be recorded and stored by the Royal Society of Medicine and may be distributed in future on various internet channels.
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