About this event

  • Date and time Tue 21 Jan 2020 from 8:30am to 22 Jan 2020 at 5:40pm
  • Location Royal Society of Medicine
  • Organised by Pathology, Pathological Society of Great Britain and Ireland

The 3rd joint RSM and Pathological Society winter meeting will give you a unique view of ongoing advances in molecular pathology and digital pathology with a focus on recent developments and themes for the future, including genetics and oncology topics.

Delegates will get an insight into exciting emerging novel technologies that are already being used, and others that are soon to be incorporated into these two cutting edge pathological disciplines. 

Finally, delegates will hear about how innovative technologies can be used to enhance pathology teaching and training at both undergraduate and postgraduate levels.

Topics include:

  • Understand and know about digital and computational pathology developments including QuPath, PathLAKE, tissue phenomics, quantitative biomarker research, and optical imaging.
  • Be able to evaluate how assessment drives learning in Pathology and appreciate the importance of role models and how to inspire trainees to become teachers.
  • Understand and know about molecular pathology developments including in colorectal cancer, endometrial pathology, melanoma, breast pathology and apoptosis.
  • Understand how different mutant cancer susceptibility genes can interact during tumour development.

Save 10% when you book to attend 2 days. The discount will be automatically applied at the checkout. 

Tickets

Early bird pricing available until 15 October 2019.

Multiday discount

Save 10% when you book to attend 2 days. The discount will be automatically applied at the checkout. 

Member

RSM Fellow
Day 1 Day 2
£126.00 Day 1
£65.00 Dinner
(optional)
£126.00 Day 2
RSM Associate
Day 1 Day 2
£48.00 Day 1
£65.00 Dinner
(optional)
£48.00 Day 2
RSM Trainee
Day 1 Day 2
£48.00 Day 1
£65.00 Dinner
(optional)
£48.00 Day 2
RSM Retired Fellow
Day 1 Day 2
£48.00 Day 1
£65.00 Dinner
(optional)
£48.00 Day 2
RSM Student
Day 1 Day 2
£0.00 Day 1
£30.00 Dinner
(optional)
£0.00 Day 2

Non - Member

Consultant / GP
Day 1 Day 2
£210.00 Day 1
£65.00 Dinner
(optional)
£210.00 Day 2
Path Soc Consultant
Day 1 Day 2
£126.00 Day 1
£65.00 Dinner
(optional)
£126.00 Day 2
AHP / Nurse / Midwife
Day 1 Day 2
£80.00 Day 1
£65.00 Dinner
(optional)
£80.00 Day 2
Trainee
Day 1 Day 2
£80.00 Day 1
£65.00 Dinner
(optional)
£80.00 Day 2
Path Soc Retired
Day 1 Day 2
£48.00 Day 1
£65.00 Dinner
(optional)
£48.00 Day 2
Path Soc Trainee
Day 1 Day 2
£48.00 Day 1
£65.00 Dinner
(optional)
£48.00 Day 2
Path Soc Other
Day 1 Day 2
£48.00 Day 1
£65.00 Dinner
(optional)
£48.00 Day 2
Student
Day 1 Day 2
£40.00 Day 1
£30.00 Dinner
(optional)
£40.00 Day 2
Path Soc Student
Day 1 Day 2
£0.00 Day 1
£30.00 Dinner
(optional)
£0.00 Day 2

Key speakers

Dr Ian Frayling

Dr Ian Frayling

Consultant in Genetic Pathology, Cardiff

Speaker's biography

Ian qualified in Clinical Medicine at Cambridge and after initial training in pathology, he studied DNA damage repair for his PhD.

In 1993, he was appointed Clinical Research Fellow in the Family Cancer Clinic at St Mark’s Hospital. There he helped to establish APC testing in familial polyposis and microsatellite instability testing in Lynch syndrome. He also helped identify the CRAC1 locus [now known to be GREM1] responsible for HMPS, and establish that the position within APC of an inherited mutation is itself a major modifier of polyposis severity.

His work now concentrates on mutation interpretation and systematic testing of incident cancers to identify hereditary cases, and he is also an assessor for the UK National External Quality Assessment Scheme in Immunohistochemistry.

He is a founder member of InSiGHT, InSiGHT’s Variant Interpretation Committee, and the Mallorca Group. In 2015 he was elected to InSiGHT Council.

Professor Ian Tomlinson

Professor Ian Tomlinson

Director of the Institute of Cancer and Genomic Sciences, University of Birmingham

Speaker's biography

Ian Tomlinson is a clinician scientist and cancer geneticist. His work is based on the discovery and analysis of cancer-causing genes, especially inherited genetic variants that predispose to cancer. Using these findings, his research extends to the identification of disease mechanisms in model systems, and to cancer evolution.

Highlights of Ian’s work include the discovery of multiple Mendelian colorectal and kidney cancer predisposition genes. This has led to the identification and characterisation of diverse mechanisms of tumorigenesis, such as activation of mTOR signalling and failure of DNA polymerase proofreading. He has also led consortia that have identified many polymorphisms that influence the risk of colorectal, endometrial and oesophageal cancers. Again, this has identified important mechanisms of tumour predisposition, most strikingly the pervasive influence of variation in bone morphogenetic protein signalling on colorectal cancer risk.

Ian’s work in cancer evolution includes both mathematical models and experimental analyses. He has focussed on the importance of selection in the Darwinian process of carcinogenesis, identifying several driver mutations under selective constraints. As a result, he has identified new models of cancer evolution, chief among them being the so-called ‘just right’ model, based on selection for an optimal, intermediate level of pathway activation in tumours.

Agenda

Day one - Tuesday 21 January 2020 21 January 2020

Registration and coffee
Welcome and introduction

Mark Arends and Simon Herrington, University of Edinburgh

Symposium: Digital and Optical Pathology

PathLAKE & computational pathology - education, analytics & discovery

Clare Verrill, Oxford

QuPath and image analysis in pathology

Pete Bankhead, Edinburgh

Tissue phenomics and biomarker discovery

Ralf Huss, Definiens, Germany

Open discussion
Refreshment Break, Trade Exhibition and Poster Viewing
Optical imaging – beyond the microscope

Simon Herrington, Edinburgh

Digital pathology & image analysis in tissue biomarker research – translating algorithms from research into clinical practice

Peter Hamilton, Philips, Belfast

Lunch and trade exhibition
Poster viewing and chairman's rounds

Education Session

Emyr Benbow, Trainees Committee and Education Committee

Assessment drives learning: pathology in the national licensing examination

Mark Gurnell, Cambridge

Seducing your successors: how to be a role model

Vimmi Passi, Warwick

Why I want to be a pathologist

Sidhant Seth, Medical Student Edinburgh and Amber Matkowski, Medical Student, Manchester

 

How trainees become teachers

Colin Melville, Manchester

Panel discussion
Refreshment Break, Trade Exhibition and Poster Viewing

Plenary Talks

4 x 15 minutes abstracts – 12 minute talk followed by 3 minutes questions and answers

Plenary Oral Presentations
Journal of Pathology: Jass Prize announcement
The Pathological Society’s Goudie Lecture

David Rubinsztein, Professor of Molecular Neurogenetics
Deputy Director, Cambridge Institute for Medical Research, UK Dementia Research Institute Professor, Academic Lead, Alzheimer’s Research UK ALBORADA Drug Discovery Institute, Honorary Consultant, Department of Medical Genetics

Thank you and closure of day 1
Society dinner

Pre-booked only

Day two - Wednesday 22 January 2020 22 January 2020

Registration and coffee
Welcome and introduction

Symposium: Molecular Pathology – The Future

Chairs - Mark Arends & Simon Herrington

Interacting mutant cancer genes

Ian Frayling

Molecular genetics of colorectal cancer

Ian Tomlinson, Birmingham/Edinburgh

Open discussion
Refreshment Break, Trade Exhibition and Poster Viewing

Symposium: Molecular Pathology – The Future

Chairs - Mark Arends and TBC

Molecular pathology of endometrial carcinoma

Tjalling Bosse, Leiden, The Netherlands

Molecular pathology of melanoma

David Adams, Senior Group Leader, Wellcome Trust Sanger Institute, Cambridge

Open discussion
‘Rapid-Fire’ Oral Presentations

5 x 5 minute presentations

Lunch, Trade Exhibition and Poster Viewing

Symposium: Molecular Pathology – The Future

Chairs - Simon Herrington and TBC

Molecular advances in apoptosis

Stephen Tait, Glasgow

Molecular pathology of breast cancer

Elena Provenzano

Open discussion and Closure of the Symposium
Refreshments

Sponsors

Location

Royal Society of Medicine, 1 Wimpole St,, Marylebone, London, London, W1G 0AE, United Kingdom