Professor Bo Jacobsson
Professor and Consultant, University of Gothenburg
About this event
- Date and time Tue 26 Jul 2022 from 9:00am to 6:10pm
- Location Online
- Organised by Paediatrics and Child Health, William Little Foundation
This live stream aims to highlight where significant advances have been and could be made in cerebral palsy prevention research in the UK and internationally.
Join UK’s first meeting dedicated solely to research into the prevention of cerebral palsy featuring contributions from international and UK research leaders. Attendees will be given a clear understanding of the latest views on the aetiology of CP, with additional focus on the epidemiology of the condition, with examples of current and new therapeutic interventions.
Want to attend in-person at the RSM? Click here to book your place.
Participants will have a greater understanding of:
- The value of MR imaging as a technology to aid the prenatal diagnosis of foetal developmental brain abnormalities
- The essential role of maternal nutrition in the development of the foetal brain, particularly around the management of obesity and DHA levels
- The value of genetic screening on aiding early detection
- The positive impact of supplements, particularly magnesium sulphate, and other examples of perinatal care to prevent neuro disabilities
Additionally, attendees will also gain insights into the new screening technologies and artificial intelligence. They'll learn how:
- Artificial intelligence is beginning to be deployed in predicting CP
- New screening technology (using light to monitor newborn brain metabolism) will help earlier detection of CP
- Analysis of the genome (particularly RNA) offers a potential path to new, preventive treatments for CP
This live stream will illustrate to UK clinical and research communities, and policy-makers that there is substantial scientific, social and economic merit in devoting a higher priority to funding research into cerebral palsy.
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Key speakers
Professor Nadia Badawi
Professor and Chair of Cerebral Palsy, Grace Centre for Newborn Care, University of Sydney
Professor Nikki Robertson
Professor of Perinatal Neuroscience, University College London
Professor Pierre Gressens
Professor of Foetal and Neonatal Neurology, King's College London
Agenda
View the programme
Welcome and introduction
Session 1: Aetiology, early detection and diagnosis
Genetic or other causation should not change the clinical diagnosis of cerebral palsy
Professor Bo Jacobsson, Professor and Consultant, University of Gothenburg
MRI in the diagnosis of fetal developmental brain abnormalities: The meridian diagnostic accuracy study
Professor Paul Griffiths, Professor of Radiology, University of Sheffield
Is the haemorrhage, ischemia and inflammation which leads to white matter damage in the developing brain linked to lipid nutrition?
Professor Michael Crawford, Director, Institute of Brain Chemistry and Human Nutrition and Visiting Professor, Imperial College London
Comfort break
Influence of maternal obesity and nutritional status on the long-term health of offspring
Professor Keith Godfrey, Professor of Epidemiology and Human Development, University of Southampton and Director, National Institute for Health Research
Panel discussion
Keynote speech: Perinatal care with a view to preventing cerebral palsy
Professor Nadia Badawi, Professor and Chair of Cerebral Palsy, Grace Centre for Newborn Care, University of Sydney
Lunch break
Session 2: Epidemiology and therapeutic intervention
A cluster randomised trial evaluating the impact of an enhanced support implementation of the precept quality improvement toolkit to increase the uptake of magnesium sulphate in pre-term deliveries for the prevention of neurodisabilities
Professor Karen Luyt, Professor in Neonatal Medicine, University of Bristol
Complementing cooling: The ongoing search for an effective adjunct to therapeutic hypothermia
Dr Tomoki Arichi, Clinical Senior Lecturer in Perinatal Imaging, King's College London
Impact of erythropoietin in the management of hypoxic ischaemic encephalopathy in resource-constrained settings: Protocol for a randomized control trial
Dr Beatrice Ezenwa, Paediatrician, University of Lagos
Randomized controlled trial of brain specific fatty acid supplementation in pregnant women increases brain volumes on MRI scans of their newborn infants
Professor Mark Johnson, Clinical Chair in Obstetrics, Imperial College London
Cell therapy for neonatal hypoxia-ischemia and cerebral palsy
Professor Nikki Robertson, Professor of Perinatal Neuroscience, University College London
Comfort break
Session 3: The future
Neuroprotection of the perinatal brain lesions: Hopes and challenges, the example of melatonin
Professor Pierre Gressens, Laboratory Director, Inserm, Université Paris Cité
The analysis of RNA, protein expression and protein interactions in human tissue, their centrality to neurological research and the prospect of the development of treatments based on these advances
Professor Henry Houlden, Professor of Neurology, University College London
Future of neuromonitoring in neonatal neurocritical care
Dr Subhabrata Mitra, Consultant Neonatologist, University College London
Towards explainable abnormal infant movements identification for the early prediction of cerebral palsy
Dr Edmond Ho, Associate Professor in Computer Science, Northumbria University
Panel discussion
Closing remarks
Close of meeting
Location
Online
Disclaimer: All views expressed in this webinar are of the speakers themselves and not of the RSM nor the speaker's organisations.
Registration for this live stream will close 2 hours prior to the start time. Late registrations will not be accepted.
