About this event

  • Date and time Wed 15 Sep 2021 from 6:00pm to 7:15pm
  • Location Online
  • Organised by Critical Care Medicine

Join us to learn about the management of common haematological malignancies seen in a critical care setting. The webinar seeks to teach students, doctors and other healthcare professionals about the theory behind CAR-T therapy and the management of patients who are undergoing it.  

This webinar brings two expert speakers to discuss aspects of haematology in critical care. Dr Eleni Tholoulitransplant director, director of GM Haem-Onc Pathway Board and consultant haematologist at Manchester University NHS Foundation Trust and Dr Victoria Metaxa, consultant in critical care and major trauma at King's College Hospital in London. She is the medical lead for the critical care outreach team of the Trust as well as the end-of-life ICU lead.

During this session, participants will be able to:

  • Understand the key concepts in CAR T-Cell therapy and be able to recognise complications
  • Gain insight into the management of patients with haematological malignancies in a critical care setting

The first talk will focus on CAR (Chimeric Antigen Receptor) T-cell therapy, a novel treatment licenced for relapsed refractory DLBCL and paediatric ALL. It requires specialised treatment and ICU plays a significant part in this process. These treatments are currently trialled for many more indications where there is no other treatment available. We will discuss the diagnosis, grading and management of cytokine release syndrome(CRS) and CAR-T related neurotoxicity(ICANS).

The second talk will focus on the management of patients with haematological malignancies in a critical care setting.  

A CPD certificate with CPD credit will be issued to those joining the webinar live as well as those who watch the recording afterwards. Certificates will be issued 7 days after the webinar to those who watch it live and after 30 days for those that watch the recording. 

This webinar is available for on-demand viewing. The webinar recording will be available for registered delegates up to 30 days after the live webinar broadcast via Zoom. The link will be sent 24 hours after the webinar takes place. 

Join in the conversation online #RSMCritCare
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Key speakers

Dr Eleni Tholouli

Consultant Haematologist, Manchester Royal Infirmary

Speaker's biography

Dr Eleni Tholouli graduated in Germany and completed her haematology specialist training in Manchester where she also undertook a PhD at Manchester University investigating prognostic molecular markers in acute myeloid leukaemia. She then consolidated her transplant experience as a Transplant Fellow at the Fred Hutchinson Research Cancer Centre in Seattle, USA, one of the world’s largest stem cell transplant centres. Her expertise covers a wide range of haemato-oncological malignancies (leukaemia, myeloma, lymphoma) and non-malignant disorders (bone marrow failures, aplastic anaemia). She is the Director of the Adult Stem Cell and Immunotherapy Unit and Haemato-Oncology Pathway Board at Manchester Cancer. She is a member of the AML working party and has authored and co-authored many publications including manuscripts and book chapters and presented at many scientific congresses.

Dr Victoria Metaxa

Intensive Care Unit Consultant

Speaker's biography

Dr Victoria Metaxa has a PhD in neurosciences and a Postgraduate Diploma in Clinical Trials. She has also awarded an MA in Medical Ethics and Palliative Care from Keele University. Victoria has participated in and led a number of international and national studies, predominantly around end-of-life in critical care. She is a member of the European Society of Intensive Care (ESICM) Ethics section, as well as of the newly founded ESICM Diversity Task Force. She is participating in several clinical ethics committees and is one of 6 members in the Legal and Ethical Advisory Group of the Intensive Care Society. Victoria has set up and leading on the haemato-oncology/ critical care provision at King’s College Hospital. Through this initiative, the collaboration and daily interactions of the two teams has significantly improved. She is a founding member of the EuroCAR-T Force, a multi-national group of Critical Care consultants aiming to accelerate clinical experience, promote research and define a working framework in the emerging field of immune cell therapy.


View the programme

Welcome and introduction

Dr Nishita Desai, Honorary Secretary, Critical Care Medicine Section, Royal Society of Medicine

The CAR to cure aggressive lymphoma and the role of intensive care unit

Dr Eleni TholouliConsultant Haematologist, Manchester Royal Infirmary

Question and answer session
Haematological malignancies in intensive care unit

Dr Victoria Metaxa, Intensive Care Unit Consultant

Question and answer session
Close of meeting



Disclaimer: All views expressed in this webinar are of the speakers themselves and not of the RSM nor the speaker's organisations. 

Special rates for difficult times  

The RSM wishes to offer healthcare professionals continued learning opportunities during the coronavirus pandemic. The RSM’s weekly COVID-19 Series webinars remain free of charge, while there will be small charges to register for other online education. These fees will enable the RSM to continue its programme of activities and will apply during the course of the pandemic. 

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