Professor Mark Hatherill
Director of South African Tuberculosis Vaccine Initiative (SATVI) & Full Member of the Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town
SATVI is a world leader in TB vaccine clinical research. Their mission is the development of new and effective vaccination strategies against tuberculosis (TB). They are testing multiple new vaccine candidates in clinical trials; and are involved with projects to address critical clinical, epidemiological, immunological and human genetic questions in TB vaccine development. Activities are within an academic context, and thus include the training of postgraduate students.
The team of over 100 staff consists of specialists in: clinical, epidemiological, human genetic and immunologic science, clinical trials, community liaison, recruitment and follow-up; data management and analysis, disease surveillance, information technology, clinical evaluation and care of participants; facility management, laboratory technology, logistics, research pharmacy management, project management, regulatory affairs, administration, study coordination and training.
Professor Hatherill’s clinical research interests have focused on design, implementation, and analysis of clinical trials of BCG vaccine and novel TB vaccines candidates; diagnostic studies of TB infection and disease in adult and paediatric study populations; and TB therapeutic clinical trials. A major new project will test targeted TB preventive therapy for high risk persons identified by a novel transcriptomic correlate of risk assay.
Further details are found here [www.satvi.uct.ac.za]