About this event

  • Date and time Tue 26 Jul 2022 from 8:30am to 7:30pm
  • Location Royal Society of Medicine
  • Organised by Paediatrics and Child Health, William Little Foundation

This joint event with the William Little Foundation aims to highlight where significant advances have been and could be made in cerebral palsy prevention research in the UK and internationally.

Join UK’s first conference dedicated solely to research into the prevention of cerebral palsy featuring contributions from international and UK research leadersAttendees will be given a clear understanding of the latest views on the aetiology of CP, with additional focus on the epidemiology of the condition, with examples of current and new therapeutic interventions.

Attendees will also benefit from the opportunity to network in-person with an international, multidisciplinary gathering of experience, skills and expertise uniquely focused on CP prevention.

Can't make it to London for this event? You can now live stream this meeting from anywhere. Click here to book the live stream.

Attendees will have a greater understanding of:

  • The value of MR imaging as a technology to aid the prenatal diagnosis of foetal developmental brain abnormalities 
  • The essential role of maternal nutrition in the development of the foetal brain, particularly around the management of obesity and DHA levels
  • The value of genetic screening on aiding early detection
  • The positive impact of supplements, particularly magnesium sulphate, and other examples of perinatal care to prevent neuro disabilities

Additionally, attendees will also gain insights into the new screening technologies and artificial intelligence. They'll learn how:

  • Artificial intelligence is beginning to be deployed in predicting CP 
  • New screening technology (using light to monitor newborn brain metabolism) will help earlier detection of CP
  • Analysis of the genome (particularly RNA) offers a potential path to new, preventive treatments for CP

This event will illustrate to UK clinical and research communities, and policy-makers that there is substantial scientific, social and economic merit in devoting a higher priority to funding research into cerebral palsy.

To find out more about the William Little Foundation, click here.

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Key speakers

Professor Bo Jacobsson

Professor and Consultant, University of Gothenburg

Professor Nadia Badawi

Professor and Chair of Cerebral Palsy, Grace Centre for Newborn Care, University of Sydney

Professor Nikki Robertson

Professor of Perinatal Neuroscience, University College London 

Professor Pierre Gressens

Professor of Foetal and Neonatal Neurology, King's College London

Agenda

View the programme

Registration, tea and coffee
Welcome and introduction

Session 1: Aetiology, early detection and diagnosis

Genetic or other causation should not change the clinical diagnosis of cerebral palsy

Professor Bo Jacobsson, Professor and Consultant, University of Gothenburg

MRI in the diagnosis of fetal developmental brain abnormalities: The meridian diagnostic accuracy study

Professor Paul Griffiths, Professor of Radiology, University of Sheffield 

Is the haemorrhage, ischemia and inflammation which leads to white matter damage in the developing brain linked to lipid nutrition?

Professor Michael Crawford, Director, Institute of Brain Chemistry and Human Nutrition and Visiting Professor, Imperial College London

Tea and coffee break
Influence of maternal obesity and nutritional status on the long-term health of offspring

Professor Keith Godfrey, Professor of Epidemiology and Human Development, University of Southampton and Director, National Institute for Health Research

Panel discussion
Keynote speech: Perinatal care with a view to preventing cerebral palsy

Professor Nadia Badawi, Professor and Chair of Cerebral Palsy, Grace Centre for Newborn Care, University of Sydney

Lunch break

Session 2: Epidemiology and therapeutic intervention

PReCePT – National implementation of magnesium sulphate for fetal neuroprotection during preterm birth

Professor Karen Luyt, Professor in Neonatal Medicine, University of Bristol

Complementing cooling: The ongoing search for an effective adjunct to therapeutic hypothermia

Dr Tomoki Arichi, Clinical Senior Lecturer in Perinatal Imaging, King's College London

Impact of erythropoietin in the management of hypoxic ischaemic encephalopathy in resource-constrained settings

Dr Beatrice Ezenwa, Paediatrician, University of Lagos

Randomized controlled trial of brain specific fatty acid supplementation in pregnant women increases brain volumes on MRI scans of their newborn infants

Professor Mark Johnson, Clinical Chair in Obstetrics, Imperial College London

Cell therapy for neonatal hypoxia-ischemia and cerebral palsy

Professor Nikki Robertson, Professor of Perinatal Neuroscience, University College London 

Tea and coffee break

Session 3: The future

Neuroprotection of the perinatal brain lesions: Hopes and challenges, the example of melatonin

Professor Pierre Gressens, Laboratory Director, Inserm, Université Paris Cité 

The analysis of RNA, protein expression and protein interactions in human tissue, their centrality to neurological research and the prospect of the development of treatments based on these advances

Professor Henry Houlden, Professor of Neurology, University College London

Presenting virtually

Future of neuromonitoring in neonatal neurocritical care

Dr Subhabrata Mitra, Consultant Neonatologist, University College London

Towards explainable abnormal infant movements identification for the early prediction of cerebral palsy

Dr Edmond Ho, Associate Professor in Computer Science, Northumbria University 

Panel discussion
Closing remarks
Close of meeting
Drinks reception

Location

Royal Society of Medicine, 1 Wimpole St, Marylebone, London, W1G 0AE, United Kingdom

Disclaimer: All views expressed in this webinar are of the speakers themselves and not of the RSM nor the speaker's organisations. 

Registration for this event will close on 25 July 2022 at 1am. Late registrations will not be accepted. 

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