Frontiers in the degenerative dementias: toward new opportunities in treatment

Monday - Tuesday  9 - 10 June 2008

Venue: The Royal Society of Medicine, 1 Wimpole Street, London, W1G 0AE

organised by the Royal Society of Medicine and The New York Academy of Medicine

Over the past decade or so, there have been major advances in our understanding of the pathogenesis of Alzheimer's disease and other degenerative dementias, leading to the prospect of the development of novel, disease-modifying treatments.
This symposium aims to examine key topics in the degenerative dementias, ranging from pathogenesis, including genetic investigations and current molecular and cellular theories, through longitudinal clinical and imaging studies, to existing therapy, current trials and potential future treatments. Lessons learnt from investigation of the mechanisms of prion-induced dementia will also be examined.

Registration Details:
Fellow: £130
Associate: £100
Student Members: £40
Trainee - Fellow: £75
Retired Fellow: £75
Non-Fellow: £240
Nurse: £125
Allied Health Professional: £125
Specialist Registrar: £125
Student: £55

CPD: 5 credits


Monday 9 June 2008

5.30 pm

Registration

5.45 pm

Welcome address
Baroness Ilora Finlay, President, RSM & Dr Jo Boufford, President, New York Academy of Medicine

Session One

6.00 pm

Keynote Lecture: The 7th age of man: solving Alzheimer's disease
Professor Dennis Selkoe, Vincent and Stella Coates Professor of Neurologic Diseases, Harvard Medical School, Brigham & Women's Hospital, USA

6.40 pm

Questions
Tuesday 10 June 2008

9.00 am

Registration & coffee

9.30 am

Welcome address

Session Two

9.35 am

Keynote Lecture: Lessons learnt from neurodegenerative dementias about the modular organisation of the cerebral cortex
Professor Martin Rossor, Institute of Neurology, University College London, UK

10.15 am

Questions

10.25 am

Why Alzheimer's is a disease of memory: the attack on synapses by Abeta oligomers (ADDLs)
Professor William Klein, Northwestern University, USA

11.00 am

Questions

11.10 am

Coffee break

Session Three

11.35 am

Genetic studies in the neurodegenerative dementias: lessons from prions
Dr Simon Mead, Institute of Neurology, University College London, UK

12.00 pm

Questions

12.10 pm

Lewy body dementia
Professor Ian McKeith, Newcastle University, UK

12.35 pm

Questions

12.45 pm

Lunch

Session Four

1.45 pm

The role of amyloid imaging in pathogenesis, diagnosis and therapy of dementia
Professor William Klunk, University of Pittsburgh, USA

2.10 pm

Questions

2.20 pm

Monitoring progression of dementia with MRI
Professor Nick Fox, Institute of Neurology, University College London, UK

2.45 pm

Questions

2.55 pm

Tea break

Session Five

3.30 pm

Trials of immunotherapy in Alzheimer's disease
Professor Norman Relkin, Cornell University, USA

3.35 pm

Questions

4.05 pm

Targeting amyloid and amyloid-associated proteins in neurodegenerative disease: lessons from systemic amyloidosis
Professor Mark Pepys, University College London Medical School, UK

4.30 pm

Questions

4.40 pm

Closing remarks and end of meeting

Related information

Contact:

Events Co-ordinator:
Carolyn Horst
Tel: +44 (0) 20 7290 3919
Fax: +44 (0) 20 7290 2989

Sponsorship Information:
Sharon Sole
Tel: +44 (0) 20 7290 3848
Fax: +44 (0) 20 7290 2989

Media Information:
Rosalind Dewar
Tel: +44 (0) 1580 764713
Mobile: +44 (0)7785 182732