Frontiers in the degenerative dementias: toward new opportunities in treatment
Monday - Tuesday 9 - 10 June 2008
Venue: The Royal Society of Medicine, 1 Wimpole Street, London, W1G 0AE
organised by the Royal Society of Medicine and The New York Academy of Medicine
Over the past decade or so, there have been major advances in our understanding of the pathogenesis of Alzheimer's disease and other degenerative dementias, leading to the prospect of the development of novel, disease-modifying treatments.
This symposium aims to examine key topics in the degenerative dementias, ranging from pathogenesis, including genetic investigations and current molecular and cellular theories, through longitudinal clinical and imaging studies, to existing therapy, current trials and potential future treatments. Lessons learnt from investigation of the mechanisms of prion-induced dementia will also be examined.
Registration Details:
Fellow: £130
Associate: £100
Student Members: £40
Trainee - Fellow: £75
Retired Fellow: £75
Non-Fellow: £240
Nurse: £125
Allied Health Professional: £125
Specialist Registrar: £125
Student: £55
CPD: 5 credits
Monday 9 June 2008 |
|
5.30 pm |
Registration |
5.45 pm |
Welcome address |
| Baroness Ilora Finlay, President, RSM & Dr Jo Boufford, President, New York Academy of Medicine | |
|
Session One |
|
6.00 pm |
Keynote Lecture: The 7th age of man: solving Alzheimer's disease |
| Professor Dennis Selkoe, Vincent and Stella Coates Professor of Neurologic Diseases, Harvard Medical School, Brigham & Women's Hospital, USA | |
6.40 pm |
Questions |
Tuesday 10 June 2008 |
|
9.00 am |
Registration & coffee |
9.30 am |
Welcome address |
|
Session Two |
|
9.35 am |
Keynote Lecture: Lessons learnt from neurodegenerative dementias about the modular organisation of the cerebral cortex |
| Professor Martin Rossor, Institute of Neurology, University College London, UK | |
10.15 am |
Questions |
10.25 am |
Why Alzheimer's is a disease of memory: the attack on synapses by Abeta oligomers (ADDLs) |
| Professor William Klein, Northwestern University, USA | |
11.00 am |
Questions |
11.10 am |
Coffee break |
|
Session Three |
|
11.35 am |
Genetic studies in the neurodegenerative dementias: lessons from prions |
| Dr Simon Mead, Institute of Neurology, University College London, UK | |
12.00 pm |
Questions |
12.10 pm |
Lewy body dementia |
| Professor Ian McKeith, Newcastle University, UK | |
12.35 pm |
Questions |
12.45 pm |
Lunch |
|
Session Four |
|
1.45 pm |
The role of amyloid imaging in pathogenesis, diagnosis and therapy of dementia |
| Professor William Klunk, University of Pittsburgh, USA | |
2.10 pm |
Questions |
2.20 pm |
Monitoring progression of dementia with MRI |
| Professor Nick Fox, Institute of Neurology, University College London, UK | |
2.45 pm |
Questions |
2.55 pm |
Tea break |
|
Session Five |
|
3.30 pm |
Trials of immunotherapy in Alzheimer's disease |
| Professor Norman Relkin, Cornell University, USA | |
3.35 pm |
Questions |
4.05 pm |
Targeting amyloid and amyloid-associated proteins in neurodegenerative disease: lessons from systemic amyloidosis |
| Professor Mark Pepys, University College London Medical School, UK | |
4.30 pm |
Questions |
4.40 pm |
Closing remarks and end of meeting |